8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
CAS: 38092-89-6
Molecular Formula: C20H21ClN2
8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine - Names and Identifiers
8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine - Physico-chemical Properties
| Molecular Formula | C20H21ClN2 |
| Molar Mass | 324.85 |
| Density | 1.205±0.06 g/cm3(Predicted) |
| Melting Point | 106-109°C |
| Boling Point | 474.3±45.0 °C(Predicted) |
| Flash Point | 240.7°C |
| Vapor Presure | 3.64E-09mmHg at 25°C |
| Appearance | neat |
| pKa | 8.67±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.622 |
8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine - Risk and Safety
| HS Code | 2933399090 |
8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine - Reference Information
| Uses | Loratadine EP impurity G is an intermediate in the synthesis of loratadine, which can be used as an anti-allergic drug. At present, the second-generation tricyclic anti-allergic drug loratadine, due to its high selectivity to peripheral H1 receptors, has no side effects of inhibiting central and peripheral choline receptors, has good clinical efficacy and safe use. First-line anti-allergic drugs have a broad market demand in my country. |
Last Update：2024-04-09 15:16:50
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